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The Microbioma... crucial in Immune Education
The world today is very different from the one our immune system evolved to anticipate — not just in what we encounter, but in when we first encounter it. Preventing autoimmune disorders may require emulating aspects of that “dirtier” world: safely bottling the kinds of microbes that protect the Russian kids, so we can give them to everyone and guide the “postmodern” immune system along a healthier path of development. 
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Chronic rhinosinusitis (CRS) is the persistent inflammation of the sinus and nasal passages lasting over 3 months. The etiology of CRS is not well understood.
Alfredo Corell's insight:
obtained findings support the theory that in some cases CRS result form an immune hyperresponsiveness to commensal organisms.
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Cells that allow good bacteria to safely colonize the intestines of newborns may cause immune suppression, explaining why they are vulnerable to infection, researchers say.
Alfredo Corell's insight:
The researchers note that the process of CD71+ immune suppression is vital for the intestines to build up healthy bacterial colonization, and this is more important than the threat of neonatal infection. However, they emphasize that further research is warranted in order to create new strategies for the protection of newborn infants against infection while still allowing the CD71+ cells to assist in developing healthy intestines.
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