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In a new study, researchers from The Scripps Research Institute and Duke University Medical Center reveal the three-dimensional structure of a crucial ion channel. Their findings shed light on the channel's possible role in immune functions such as detecting infection and inflammation. 
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The new study was published Jan. 18, 2016, in the journal Nature Structural and Molecular Biology.
An Important Sensor
Lander and his colleagues focused on an ion channel called the transient receptor potential vanilloid-2 (TRPV2), which resides within the membranes of cells throughout the body. Previous research had suggested TRPV2 was involved in sensing physical stresses, such as changes in pressure and temperature, as well as in detecting immune challenges and activating the immune system's T cells.